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Recent Advances in Ionic Liquids in Biomedicine

2021/07/10 by Alexander M. Curreri, Samir Mitragotri, Eden E. L. Tanner
Chemical Engineering · Engineering · #Electrochemical sensors and biosensors #Innovative Microfluidic and Catalytic Techniques Innovation #Ionic liquids properties and applications

paper · doi:10.1002/advs.202004819

openalex publication_date 2021/07/10 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/29

Abstract

The use of ionic liquids and deep eutectic solvents in biomedical applications has grown dramatically in recent years due to their unique properties and their inherent tunability. This review will introduce ionic liquids and deep eutectics and discuss their biomedical applications, namely solubilization of drugs, creation of active pharmaceutical ingredients, delivery of pharmaceuticals through biological barriers, stabilization of proteins and other nucleic acids, antibacterial agents, and development of new biosensors. Current challenges and future outlooks are discussed, including biocompatibility, the potential impact of the presence of impurities, and the importance of understanding the microscopic interactions in ionic liquids in order to design task-specific solvents.

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