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Gut Bacteroides species in health and disease

2021/01/01 by Hassan Zafar, Milton H. Saier · 10 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Diet and metabolism studies #Gastrointestinal motility and disorders #Gut microbiota and health

paper · pdf · doi:10.1080/19490976.2020.1848158

openalex publication_date 2021/01/01 · openalex created_date 2021/02/15 · openalex updated_date 2026/07/29

Abstract

The functional diversity of the mammalian intestinal microbiome far exceeds that of the host organism, and microbial genes contribute substantially to the well-being of the host. However, beneficial gut organisms can also be pathogenic when present in the gut or other locations in the body. Among dominant beneficial bacteria are several species of Bacteroides, which metabolize polysaccharides and oligosaccharides, providing nutrition and vitamins to the host and other intestinal microbial residents. These topics and the specific organismal and molecular interactions that are known to be responsible for the beneficial and detrimental effects of Bacteroides species in humans comprise the focus of this review. The complexity of these interactions will be revealed.

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