Walks of molecular motors in two and three dimensions

2002/03/11 by Theo M. Nieuwenhuizen, Stefan Klumpp, Reinhard Lipowsky · 2 citations
Biochemistry, Genetics and Molecular Biology · Physics and Astronomy · #Diffusion and Search Dynamics #Spectroscopy and Quantum Chemical Studies #cond-mat.stat-mech #physics.bio-ph #q-bio.SC #stochastic dynamics and bifurcation

paper · pdf · doi:10.1209/epl/i2002-00662-4

published as Europhys. Lett. 58, 468 (2002) · 7 pages, 2 figures, to be published in Europhys. Lett

arxiv created 2002/03/11 · openalex publication_date 2002/05/01 · arxiv updated 2009/11/30 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/30

Abstract

Molecular motors interacting with cytoskeletal filaments undergo peculiar random walks consisting of alternating sequences of directed movements along the filaments and diffusive motion in the surrounding solution. An ensemble of motors is studied which interacts with a single filament in two and three dimensions. The time evolution of the probability distribution for the bound and unbound motors is determined analytically. The diffusion of the motors is strongly enhanced parallel to the filament. The analytical expressions are in excellent agreement with the results of Monte Carlo simulations.

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• Random walks of molecular motors arising from diffusional encounters with immobilized filaments
• Asymmetric simple exclusion processes with diffusive bottlenecks

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