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Cold and Warm Denaturation of Proteins

2002/01/16 by Guido Caldarelli, Paolo De Los Rios · 1 citation
Physics and Astronomy · Biochemistry, Genetics and Molecular Biology · #cond-mat.stat-mech #cond-mat.soft #q-bio

paper · pdf

published as J. Biol. Phys. 27, 229 (2001)

arxiv created 2002/01/16 · arxiv updated 2009/11/30

Abstract

We introduce a simplified protein model where the water degrees of freedom appear explicitly (although in an extremely simplified fashion). Using this model we are able to recover both the warm and the cold protein denaturation within a single framework, while addressing important issues about the structure of model proteins.

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