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A standardized clinical database for research in Chagas disease: The NHEPACHA network

2024/08/15 by Adriana González Martínez, Irene Losada, Juan Carlos Gabaldón-Figueira +15 · 1 voice
Medicine · #Trypanosoma species research and implications

paper · doi:10.1371/journal.pntd.0012364

openalex publication_date 2024/08/15 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/31

Abstract

The NHEPACHA Iberoamerican Network, founded on the initiative of a group of researchers from Latin American countries and Spain, aims to establish a research framework for Chagas disease that encompasses diagnosis and treatment. For this purpose, the network has created a questionnaire to gather relevant data on epidemiological, clinical, diagnostic, and therapeutic aspects of the disease. This questionnaire was developed based on a consensus of expert members of the network, with the intention of collecting high-quality standardized data, which can be used interchangeably by the different research centers that make up the NHEPACHA network. Furthermore, the network intends to offer a clinical protocol that can be embraced by other researchers, facilitating comparability among published studies, as well as the development of therapeutic response and progression markers.

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