1966/07/01 by PHILIP M. MARDEN, Philip M. Marden
Biochemistry, Genetics and Molecular Biology · Medicine · #Genetic and rare skin diseases. #Polyomavirus and related diseases #Vascular Malformations and Hemangiomas
paper · doi:10.1001/archpedi.1966.02090100115018
crossref issued 1966/07/01 · crossref published 1966/07/01 · crossref published-print 1966/07/01 · openalex publication_date 1966/07/01 · crossref created 2011/11/29 · crossref deposited 2023/04/07 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/30 · crossref indexed 2026/07/30
IN 1963 Feuerstein and Mims reported two cases of a new neurocutaneous syndrome with linear nevus sebaceus, convulsions, and mental retardation.<sup>1</sup>Two additional cases with this triad have now been observed.<sup>2,3</sup>Recently, the authors have had the opportunity to study a child who has this new syndrome in a more severe form than has heretofore been described. The purpose of this paper is to further define this entity and to call attention to the wide spectrum of anomalies that may occur. <h3>Report of a Case</h3> The patient was the product of a 38-week gestation of an 18-year-old mother and a 29-year-old father. The pregnancy was complicated by vaginal bleeding in the fifth month, by slightly elevated blood pressure, and by some ankle edema in the eighth month. Furthermore, during the fourth month the mother developed vaginal molluscum contagiosum which was confirmed by biopsy, but was not treated. The