2023/02/14 by Zhi-Zhong Deng, Ya-Hui Chen, Yahui Chen
Medicine · #Spinal Cord Injury Research
paper · pdf · doi:10.31083/j.jin2202031
openalex publication_date 2023/02/14 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/29
Spinal cord injury is a serious and devastating condition. Recently, research into microRNAs (miRNAs) has become increasingly exhaustive and it has been determined that they are closely related to the pathophysiological processes of spinal cord injury. They participate in the regulation of the inflammatory response of spinal cord injury, the death of neuronal cells, and the repair of neural functions, which are related to the recovery of spinal cord injury. This review focuses on the relationship between miRNA and spinal cord injury, lists miRNA-324-5p, miRNA-221 and miRNA-124, which are helpful for the repair of spinal cord injury, and finally summarizes the current research progress of miRNA-based therapies, so as to provide a foundational reference for clinical and scientific researchers.