2014/08/16 by Nayara Zuchi, Letícia Borges da Silva Heinen, Marcelo Adriano Mendes dos Santos +2 · 3 citations
Medicine · #Mosquito-borne diseases and control #Viral Infections and Outbreaks Research #Viral Infections and Vectors
paper · pdf · doi:10.1590/0074-0276140108
openalex publication_date 2014/08/16 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/25
Mayaro virus (MAYV) is frequently reported in Pan-Amazonia. The aim of this study was to investigate the circulation of alphaviruses during a dengue outbreak in the state of Mato Grosso, Brazil. Serum samples from dengue-suspected patients were subjected to multiplex semi-nested reverse transcriptase polymerase chain reaction for 11 flaviviruses and five alphaviruses, to nucleotide sequencing and to viral isolation. MAYV was detected in 15 (2.5%) of 604 patients. Twelve were co-infected with dengue virus 4, which was isolated from 10 patients. The molecular detection of MAYV in dengue-suspected patients suggests that other arboviruses may be silently circulating during dengue outbreaks in Brazil.