1992/01/01 by Sarah M. Ozawa, Sarah Ozawa, David Sanchez-Migallon Guzman +8
Agricultural and Biological Sciences · Arts and Humanities · Medicine · Nursing · #Cardiovascular Conditions and Treatments #Rabbits: Nutrition, Reproduction, Health #Spanish Culture and Identity #Vitamin K Research Studies
paper · pdf · doi:10.2460/ajvr.21.03.0032
openalex publication_date 1992/01/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28
Plasma concentrations of pimobendan were lower than previously reported for dogs and cats, despite administration of higher doses, and had longer time to maximum concentration and half-life. Based on this study, 2 mg/kg of pimobendan in a critical care feeding formulation should maintain above a target plasma concentration for 12 to 24 hours. However, further studies evaluating multiple-dose administration as well as pharmacodynamic studies and clinical trials in rabbits with congestive heart failure are needed to determine accurate dose and frequency recommendations.