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Click-ready iridium( iii ) complexes as versatile bioimaging probes for bioorthogonal metabolic labeling

2024/12/03 by Vincent Rigolot, Clémence Simon, Aude Bouchet +9 · 2 voices
Chemistry · Biochemistry, Genetics and Molecular Biology · Medicine · #Click Chemistry and Applications #Advanced Biosensing Techniques and Applications #Monoclonal and Polyclonal Antibodies Research

paper · pdf · doi:10.1039/d4cb00255e

Abstract

) and inductively coupled plasma mass spectrometry (for routine quantification on cell populations with high statistical confidence). The synthesized Ir(iii) complexes were utilized in single labeling experiments, as well as in dual click-labeling experiments utilizing two distinct monosaccharide reporters relevant to the same metabolic pathway.

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