2002/05/03 by D. L. Woolard, Dwight Woolard, Tatiana Globus +18 · 1 citation
Biochemistry, Genetics and Molecular Biology · Engineering · Physics and Astronomy · #DNA and Nucleic Acid Chemistry #Gyrotron and Vacuum Electronics Research #Terahertz technology and applications
paper · doi:10.1103/physreve.65.051903
openalex publication_date 2002/05/03 · openalex created_date 2025/10/10 · openalex updated_date 2026/06/11
A detailed investigation of phonon modes in DNA macromolecules is presented. This work presents experimental evidence to confirm the presence of multiple dielectric resonances in the submillimeter-wave spectra (i.e., approximately 0.01-10 THz) obtained from DNA samples. These long-wave (i.e., approximately 1-30 cm(-1)) absorption features are shown to be intrinsic properties of the particular DNA sequence under study. Most importantly, a direct comparison of spectra between different DNA samples reveals a large number of modes and a reasonable level of sequence-specific uniqueness. This work establishes the initial foundation for the future use of submillimeter-wave spectroscopy in the identification and characterization of DNA macromolecules.