Development and Validation of a Sulfa Antibiotic Allergy Clinical Decision Rule

2023/06/05 by Jamie Waldron, Morgan J. Rose, Sara Vogrin +4 · 2 voices · 4 citations
Medicine · #Asthma and respiratory diseases #Drug-Induced Adverse Reactions #Pneumocystis jirovecii pneumonia detection and treatment

paper · pdf · doi:10.1001/jamanetworkopen.2023.16776

openalex publication_date 2023/06/05 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/22

Abstract

This cohort study describes the adaptation of a widely used penicillin allergy clinical decision tool for evaluation of trimethoprim-sulfamethoxazole allergy.

Cited by

• Development and validation of a cephalosporin allergy clinical decision rule
• ESCMID clinical guidelines on the evaluation and management of a reported antibiotic allergy
• Point prevalence survey of antibiotic allergies in hospitalized patients
• Direct Oral Challenge for Penicillin Allergy: The International Network of Antibiotic Allergy Nations (iNAAN) Study

Discussions

• TMPSMX rechallenge and allergy delabeling should be done much more often, e.g. using SULF-FAST score @trubianojason.bsky.social doi.org/10.1001/jama... [bsky, 6 points, 0 comments]
• The actual paper is here: doi.org/10.1001/jama... The components are the same as PENFAST. Score <3: 5% risk of allergy Score 3+: 20% risk. Haven’t seen much more on it since this paper, but yo [bsky, 5 points, 3 comments]

Related

• Development and validation of a cephalosporin allergy clinical decision rule
• ESCMID clinical guidelines on the evaluation and management of a reported antibiotic allergy
• National expert consensus on the management of antibiotic prophylaxis in surgical patients with a penicillin allergy label based on the Delphi method
• Point prevalence survey of antibiotic allergies in hospitalized patients
• Peri‐operative allergy: continuing to navigate uncertainty