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Reorganization of budding yeast cytoplasm upon energy depletion

2020/06/01 by Guendalina Marini, Elisabeth Nüske, Weihua Leng +2

paper · doi:10.1091/mbc.e20-02-0125

Abstract

Yeast responds to energy depletion with a rapid cytoplasmic reorganization that includes cytosol compaction and de novo formation of membraneless compartments. The reversible polymerization of eIF2B into filamentous assemblies suggests a mechanism of translational control that allows cells to move quickly back and forth between response states.

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