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A cross-sectional survey of exercise and dietary preferences for individuals with treatment-resistant schizophrenia

2026/03/26 by Diana Atmad, James O’Donoghue, Brian Hallahan

paper · doi:10.1017/ipm.2026.10184

Abstract

Abstract Introduction: Individuals with schizophrenia experience high rates of metabolic syndrome and premature mortality, largely driven by antipsychotic-induced weight gain and sedentary behaviour. Aerobic exercise and dietary interventions can positively impact quality of life and physical health indices. This study examines perspectives on engagement in aerobic exercise and diet in a cohort of participants treated with clozapine. Methods: Semi-structured interviews were conducted with 43 individuals attending a clozapine clinic at University hospital Galway. Participants’ perspectives regarding engagement in aerobic exercise and dietary modification were attained with chi-squared and regression analyses utilised to determine associations with functioning, symptomatology, and demographic data. Thematic analyses were utilised to assess qualitative data. Results: Twenty-nine individuals (67.4%) expressed a preference for engaging in additional exercise with brisk walking most favoured ( n = 25, 58.1%) with patients stating a preference for home based or individualised interventions (i.e. walking) except for dancing. Participants who engaged in 2 = 6.38, p = 0.04). Themes pertaining to engagement in exercise included importance of self-motivation ( n = 8), benefits for health ( n = 5), and environmental barriers to participation ( n = 6) with themes pertaining to dietary change included willingness to change diet for health benefits ( n = 21), and amotivation for change ( n = 2). Conclusion: Embedding tailored, exercise, and dietary programmes provided as part of patient’s routine mental health care would be welcomed by patients. Future studies evaluating potential benefits of exercise and diet interventions across functioning, physical and mental health parameters are suggested.

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