DrosophilaMushroom Body Mutants are Deficient in Olfactory Learning

1985/01/01 by Martin Heisenberg, Alexander Borst, Sibylle Wagner +1 · 11 citations
Agricultural and Biological Sciences · Neuroscience · #Animal Behavior and Reproduction #Insect Utilization and Effects #Neurobiology and Insect Physiology Research

paper · doi:10.3109/01677068509100140

openalex publication_date 1985/01/01 · openalex created_date 2016/06/24 · openalex updated_date 2026/07/28

Abstract

Two Drosophila mutants are described in which the connections between the input to and the output from the mushroom bodies is largely interrupted. In all forms of the flies (larva, imago, male, female) showing the structural defect, olfactory conditioning is impaired. Learning is completely abolished when electroshock is used as reinforcement and partially suppressed in reward learning with sucrose. No influence of the mushroom body defect on the perception of the conditioning stimuli or on spontaneous olfactory behavior is observed. The defect seems not to impair learning of color discrimination tasks or operant learning involving visual cues.

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