Mnemonic Similarity Task: A Tool for Assessing Hippocampal Integrity

2019/10/06 by Shauna M. Stark, C. Brock Kirwan, Craig E.L. Stark · 1 voice · 6 citations
Computer Science · Neuroscience · Psychology · #Child and Animal Learning Development #Cognitive Science and Mapping #Memory and Neural Mechanisms

paper · doi:10.1016/j.tics.2019.08.003

openalex publication_date 2019/10/06 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/29

Citations

• False recognition produced by implicit verbal responses.
• A task to assess behavioral pattern separation (BPS) in humans: Data from healthy aging and mild cognitive impairment
• Simple memory: a theory for archicortex
• Mild Cognitive Impairment
• Pattern separation and pattern completion in Alzheimer's disease: Evidence of rapid forgetting in amnestic mild cognitive impairment
• Structural and functional correlates of behavioral pattern separation in the hippocampus and medial temporal lobe
• Pattern separation of emotional information in hippocampal dentate and CA3
• Stability of age-related deficits in the mnemonic similarity task across task variations.
• Evidence for area CA1 as a match/mismatch detector: A high‐resolution fMRI study of the human hippocampus
• Perceptual versus conceptual interference and pattern separation of verbal stimuli in young and older adults
• Computational constraints suggest the need for two distinct input systems to the hippocampal CA3 network
• Computational analysis of the role of the hippocampus in memory
• Repetition related changes in activation and functional connectivity in hippocampus predict subsequent memory
• Pattern separation deficits associated with increased hippocampal CA3 and dentate gyrus activity in nondemented older adults
• Contributions of human hippocampal subfields to spatial and temporal pattern separation
• Greater loss of object than spatial mnemonic discrimination in aged adults

Cited by

• Dissociative Effects of Age on Neural Differentiation at the Category and Item Levels
• Pattern separation beyond the hippocampus: A<scp>high‐resolution whole‐brain</scp>investigation of mnemonic discrimination in healthy adults
• Intrinsic functional connectivity in the default mode network predicts mnemonic discrimination: A connectome‐based modeling approach
• A compressed code for memory discrimination
• Deficits in Behavioral and Neuronal Pattern Separation in Temporal Lobe Epilepsy
• Hippocampal formation–cortical high-fidelity memory networks in healthy older adults during the mnemonic discrimination task

Discussions

• How do brains manage it? For a long while, the hippocampus has been known to be involved (thanks to @brockkirwan.com, @mikeyassa.bsky.social and others) - eg individuals with hippocampal damage are im [bsky, 6 points, 1 comments]