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RNAi in Plants: An Argonaute-Centered View

2016/02/01 by Xiaofeng Fang, Yijun Qi
Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · #Plant Molecular Biology Research #RNA Research and Splicing #RNA modifications and cancer

paper · doi:10.1105/tpc.15.00920

openalex publication_date 2016/02/01 · openalex created_date 2016/06/24 · openalex updated_date 2026/08/01

Abstract

Argonaute (AGO) family proteins are effectors of RNAi in eukaryotes. AGOs bind small RNAs and use them as guides to silence target genes or transposable elements at the transcriptional or posttranscriptional level. Eukaryotic AGO proteins share common structural and biochemical properties and function through conserved core mechanisms in RNAi pathways, yet plant AGOs have evolved specialized and diversified functions. This Review covers the general features of AGO proteins and highlights recent progress toward our understanding of the mechanisms and functions of plant AGOs.

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