Selective phosphodiesterase 4 inhibitor roflumilast reduces inflammation and lung injury in models of betacoronavirus infection in mice

2025/01/25 by Vinícius Amorim Beltrami, Flávia Rayssa Braga Martins, Débora Gonzaga Martins +16 · 1 citation
Biochemistry, Genetics and Molecular Biology · Medicine · #Phosphodiesterase function and regulation #Protein Kinase Regulation and GTPase Signaling #Pulmonary Hypertension Research and Treatments

paper · doi:10.1007/s00011-024-01985-3

openalex publication_date 2025/01/25 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/03

Citations

• Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
• Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study
• SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
• Clinical and immunological features of severe and moderate coronavirus disease 2019
• Targeting potential drivers of COVID-19: Neutrophil extracellular traps
• Remdesivir for the Treatment of Covid-19 — Final Report
• Dexamethasone in Hospitalized Patients with Covid-19
• Angiotensin-(1–7) decreases inflammation and lung damage caused by betacoronavirus infection in mice

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