Recent Advances and Perspectives in Transition Metal‐Catalyzed 1,4‐Functionalizations of Unactivated 1,3‐Enynes for the Synthesis of Allenes

2019/10/26 by Liang Fu, Steffen Greßies, Pinhong Chen +1 · 3 citations
Chemistry · #Asymmetric Hydrogenation and Catalysis #Catalytic Alkyne Reactions #Catalytic C–H Functionalization Methods

paper · doi:10.1002/cjoc.201900277

openalex publication_date 2019/10/26 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/30

Abstract

Classic methods for the synthesis of allenes usually introduce only one functional group into products. In this review, we highlight the recent advances and perspectives in the synthesis of allenes by transition metal‐catalyzed 1,4‐functionalization of unactivated 1,3‐enynes.

Cited by

• Photoinduced Merging with Copper‐ or Nickel‐Catalyzed 1,4‐Cyanoalkylarylation of 1,3‐Enynes to Access Multiple Functionalizatized Allenes in Batch and Continuous Flow
• One Stone Two Birds—Enantioselective Bimetallic Catalysis for α‐Amino Acid Derivatives with an Allene Unit
• Photoredox copper-catalyzed regioselective syntheses of allenols via HAT-mediated propargyl radical generation

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