Type V CRISPR-Cas Cpf1 endonuclease employs a unique mechanism for crRNA-mediated target DNA recognition

2016/07/22 by Pu Gao, Hui Yang, Kanagalaghatta R Rajashankar +2 · 1 citation

paper · doi:10.1038/cr.2016.88

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• And… cut! – how conformational regulation of CRISPR-Cas effectors directs nuclease activity