Neutrophil intrinsic and extrinsic regulation of NETosis in health and disease

2022/11/05 by Valentina Poli, Ivan Zanoni · 1 voice · 6 citations
Immunology and Microbiology · Medicine · Biochemistry, Genetics and Molecular Biology · #Neutrophil, Myeloperoxidase and Oxidative Mechanisms #Vasculitis and related conditions #Inflammasome and immune disorders

paper · doi:10.1016/j.tim.2022.10.002

Citations

• Histone hypercitrullination mediates chromatin decondensation and neutrophil extracellular trap formation
• SARS-CoV-2–triggered neutrophil extracellular traps mediate COVID-19 pathology

Cited by

• CXCR2 blockade overcomes the NETosis-mediated resistance to MEK inhibition in pancreatic cancer models
• Epigenetic regulation of innate immune dynamics during inflammation
• Neutrophil Extracellular Traps (NETs) in health and disease
• ROS homeostasis in cell fate, pathophysiology, and therapeutic interventions
• Placental endothelial ferroptosis induced by neutrophil NETosis leads to intrauterine growth restriction in dengue virus infection
• Neutrophil biology and fate reprogramming in bacterial infections: mechanisms, plasticity, and therapeutic targeting

Discussions

• We then dig into the #epigenetic control of #NET induction by neutrophils during sepsis & lung infections with @valepo.bsky.social @cp-iscience.bsky.social, we recently discussed also @cp-trendsmicrob [bsky, 6 points, 1 comments]