A Bayesian approach to assess interaction between known risk factors: the risk of lung cancer from exposure to asbestos and smoking

2007/08/14 by D. Wraith, Darren Wraith, Kerrie Mengersen +1
Biochemistry, Genetics and Molecular Biology · Environmental Science · Medicine · #Air Quality and Health Impacts #Carcinogens and Genotoxicity Assessment #Occupational and environmental lung diseases

paper · doi:10.1177/0962280206075525

openalex publication_date 2007/08/14 · openalex created_date 2025/10/10 · openalex updated_date 2026/05/21

Abstract

We review the literature on the combined effect of asbestos exposure and smoking on lung cancer, and explore a Bayesian approach to assess evidence of interaction. Previous approaches have focussed on separate tests for an additive or multiplicative relation. We extend these approaches by exploring the strength of evidence for either relation using approaches which allow the data to choose between both models. We then compare the different approaches.

Citations

• Proportion of lung cancers due to occupational exposure

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