Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder

2016/11/10 by Vladimir N. Uversky, Vladimir N Uversky · 8 citations
Biochemistry, Genetics and Molecular Biology · #Nuclear Structure and Function #RNA Research and Splicing #RNA modifications and cancer

paper · doi:10.1016/j.sbi.2016.10.015

openalex publication_date 2016/11/10 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/25

Citations

• What is the total number of protein molecules per cell volume? A call to rethink some published values
• Why are ?natively unfolded? proteins unstructured under physiologic conditions?
• Macromolecular crowding: obvious but underappreciated
• Experimental models for dynamic compartmentalization of biomolecules in liquid organelles: Reversible formation and partitioning in aqueous biphasic systems

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• Protein Phase Separation: A New Phase in Cell Biology
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• First-generation predictors of biological protein phase separation