The α7 nicotinic acetylcholine receptor ligands methyllycaconitine, NS6740 and GTS-21 reduce lipopolysaccharide-induced TNF-α release from microglia

2012/08/10 by Morten S. Thomsen, Jens D. Mikkelsen
Biochemistry, Genetics and Molecular Biology · Neuroscience · #Nicotinic Acetylcholine Receptors Study #Receptor Mechanisms and Signaling #Vagus Nerve Stimulation Research

paper · doi:10.1016/j.jneuroim.2012.07.006

openalex publication_date 2012/08/10 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28

Citations

• Microglial α7 nicotinic acetylcholine receptors drive a phospholipase C/IP3pathway and modulate the cell activation toward a neuroprotective role
• Nicotinic receptor stimulation protects nigral dopaminergic neurons in rotenone‐induced Parkinson's disease models