New tricks by an old dogma: Mechanisms of the Organizational / Activational Hypothesis of steroid-mediated sexual differentiation of brain and behavior

2009/05/01 by Margaret M. McCarthy, Christopher L. Wright, Jaclyn M. Schwarz · 29 citations
Biochemistry, Genetics and Molecular Biology · Medicine · Psychology · #Estrogen and related hormone effects #Hypothalamic control of reproductive hormones #Neuroendocrine regulation and behavior

paper · doi:10.1016/j.yhbeh.2009.02.012

Cited by

• Sex diversity in the 21st century: Concepts, frameworks, and approaches for the future of neuroendocrinology
• Endocrine disruption by dietary phyto-oestrogens: impact on dimorphic sexual systems and behaviours
• Gonadal and Nongonadal Regulation of Sex Differences in Hypothalamic Kiss1 Neurones
• Cellular mechanisms of estradiol-mediated sexual differentiation of the brain
• Gonadal and nongonadal regulation of sex differences in hypothalamic Kiss1 neurones. [europepmc]
• Hormonally mediated epigenetic changes to steroid receptors in the developing brain: implications for sexual differentiation. [europepmc]
• Cellular mechanisms of estradiol-mediated sexual differentiation of the brain. [europepmc]
• Early prenatal stress epigenetically programs dysmasculinization in second-generation offspring via the paternal lineage. [europepmc]
• Endocrine disrupters: a review of some sources, effects, and mechanisms of actions on behaviour and neuroendocrine systems. [europepmc]
• Male or Female? Brains are Intersex. [europepmc]
• Sex differences in microRNA regulation of gene expression: no smoke, just miRs. [europepmc]
• Sex differences in stress-induced social withdrawal: independence from adult gonadal hormones and inhibition of female phenotype by corncob bedding. [europepmc]
• Microglia are essential to masculinization of brain and behavior. [europepmc]
• Regulatory decisions on endocrine disrupting chemicals should be based on the principles of endocrinology. [europepmc]
• Sex specific impact of perinatal bisphenol A (BPA) exposure over a range of orally administered doses on rat hypothalamic sexual differentiation. [europepmc]
• Human infertility: are endocrine disruptors to blame? [europepmc]
• Sex-specific Esr2 mRNA expression in the rat hypothalamus and amygdala is altered by neonatal bisphenol A exposure. [europepmc]
• Endocrine-disrupting actions of PCBs on brain development and social and reproductive behaviors. [europepmc]
• Sex differences in mood disorders: perspectives from humans and rodent models. [europepmc]
• An examination of sex differences in the effects of early-life opiate and alcohol exposure. [europepmc]
• Sex differences in microglial colonization and vulnerabilities to endocrine disruption in the social brain. [europepmc]
• Endocrine disruption by dietary phyto-oestrogens: impact on dimorphic sexual systems and behaviours. [europepmc]
• Estrogen receptor alpha is required in GABAergic, but not glutamatergic, neurons to masculinize behavior. [europepmc]
• Mouse MRI shows brain areas relatively larger in males emerge before those larger in females. [europepmc]
• Sex Differences and the Effects of Estradiol on Striatal Function. [europepmc]
• Integrative structural, functional, and transcriptomic analyses of sex-biased brain organization in humans. [europepmc]
• Sex differences in traumatic brain injury: a multi-dimensional exploration in genes, hormones, cells, individuals, and society. [europepmc]
• Autism Spectrum Disorder Genetics and the Search for Pathological Mechanisms. [europepmc]
• Large-Scale Transcriptomics Studies Provide Insight Into Sex Differences in Depression. [europepmc]