Incorporating the biphasic system to GIS-α Improves In vivo prediction for low solubility drugs

2025/04/23 by Marvin D. Naing, Marvin Duco Naing, Yasuhiro Tsume
Chemistry · Engineering · Medicine · Pharmacology, Toxicology and Pharmaceutics · #Analytical Chemistry and Chromatography #Biochemical engineering #Biology #Biotechnology #Chemistry #Chromatography #Drug Solubulity and Delivery Systems #Drug Transport and Resistance Mechanisms #Engineering #In vivo #Medicine #Organic chemistry #Pharmaceutical sciences #Pharmaceutical technology #Pharmacology #Solubility

paper · doi:10.1016/j.ejpb.2025.114724

openalex publication_date 2025/04/23 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/30

Citations

• Overcoming sink limitations in dissolution testing: a review of traditional methods and the potential utility of biphasic systems
• The Biopharmaceutics Classification System: Subclasses for in vivo predictive dissolution (IPD) methodology and IVIVC
• Bioavailability Enhancement Techniques for Poorly Aqueous Soluble Drugs and Therapeutics