A Facile Synthesis of Benzofuroisocoumarins from C-2 Arylated 1,3-Indanediones

2006/01/01 by Animesh Pramanik, Suven Das, Roland Fröhlich
Biochemistry, Genetics and Molecular Biology · Chemistry · #Synthesis and Biological Activity #Synthesis and Reactions of Organic Compounds #Synthesis and Biological Evaluation

paper · doi:10.1055/s-2006-926226

Abstract

Refluxing 2-hydroxy-2-(2'-hydroxy-aryl/naphthyl)-1,3-indanediones in ethyleneglycol with a catalytic amount of triethylamine produces benzofuroisocoumarins after a short reaction time (15 min) in very good yields.

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