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Rapid Assembly of Molecular Complexity from Simple Enamides

2020/03/02 by Georg Manolikakes, Philipp Kramer
Biochemistry, Genetics and Molecular Biology · Chemistry · #Advanced Synthetic Organic Chemistry #Chemical Synthesis and Analysis #Synthetic Organic Chemistry Methods

paper · doi:10.1055/s-0039-1690841

openalex publication_date 2020/03/02 · openalex created_date 2025/10/10 · openalex updated_date 2026/06/11

Abstract

The efficient assembly of structurally complex molecules containing multiple continuous stereogenic centers still constitutes a tremendous challenge for any synthetic organic chemist. In this article, we briefly summarize our recent advances in the utilization of enamides as versatile building blocks for the rapid and highly stereoselective construction of different molecular scaffolds containing up to five continuous stereocenters.

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