MDA-MB-231 breast cancer cells fuel osteoclast metabolism and activity: A new rationale for the pathogenesis of osteolytic bone metastases

2017/09/01 by Silvia Lemma, Gemma Di Pompo, Paolo E. Porporato +6
Biochemistry, Genetics and Molecular Biology · Medicine · #Bone Metabolism and Diseases #Bone health and treatments #Cancer, Hypoxia, and Metabolism

paper · doi:10.1016/j.bbadis.2017.08.030

openalex publication_date 2017/09/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/30

Citations

• Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice
• Lactate Influx through the Endothelial Cell Monocarboxylate Transporter MCT1 Supports an NF-κB/IL-8 Pathway that Drives Tumor Angiogenesis