Fluorine-19 labeling of the tryptophan residues in the G protein-coupled receptor NK1R using the 5-fluoroindole precursor in Pichia pastoris expression

2024/03/30 by Benxun Pan, Canyong Guo, Dongsheng Liu +1
Biochemistry, Genetics and Molecular Biology · #Fungal and yeast genetics research #Ion channel regulation and function #Receptor Mechanisms and Signaling

paper · doi:10.1007/s10858-024-00439-6

openalex publication_date 2024/03/30 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/29

Citations

• Structure-Function of the G Protein–Coupled Receptor Superfamily
• Attenuated T 2 relaxation by mutual cancellation of dipole–dipole coupling and chemical shift anisotropy indicates an avenue to NMR structures of very large biological macromolecules in solution
• 19F NMR: A promising tool for dynamic conformational studies of G protein-coupled receptors