2009/06/30 by Wei Li, Shisheng Wang, Jiatao Feng +7
Biochemistry, Genetics and Molecular Biology · Medicine · #Biochemical effects in animals #Curcumin's Biomedical Applications #Natural product bioactivities and synthesis
paper · doi:10.1002/mrc.2478
openalex publication_date 2009/06/30 · openalex created_date 2016/06/24 · openalex updated_date 2026/07/28
Thirteen curcuminoids (1-13) were isolated from the rhizomes of Curcuma longa. Among them, 1,5-dihydroxy-1,7-bis(4-hydroxyphenyl)-4,6-heptadiene-3-one (1), 1,5-dihydroxy-1-(4-hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)-4,6-heptadiene-3-one (2), 1,5-dihydroxy-1-(4-hydroxyphenyl)-7-(4-hydroxy-3-methoxyphenyl)-4,6-heptadiene-3-one (3), and 3-hydroxy-1,7-bis-(4-hydroxyphenyl)-6-heptene-1,5-dione (4) are new compounds, and 1-(4-hydroxyphenyl)-7-(3, 4-dihydroxyphenyl)-1, 6-heptadiene-3, 5-dione (5) is isolated from natural sources for the first time. The structures of these compounds were elucidated by extensive spectroscopic analyses, especially 1D and 2D NMR spectroscopy. The (13)C NMR data and complete (1)H and (13)C NMR assignments of some known compounds are reported for the first time. In addition, the errors of (1)H and (13)C assignments reported in the literature were corrected.