The potential of food-derived bioactive peptides in managing sarcopenia: Identification, structure, mechanism of action, clinical perspective, practical and safety considerations

2026/02/11 by Mehdi Nikoo, Xueqian Guo, Amin Zhang +5
Biochemistry, Genetics and Molecular Biology · Medicine · #Protein Hydrolysis and Bioactive Peptides #Nutrition and Health in Aging #GDF15 and Related Biomarkers

paper · doi:10.1016/j.tifs.2026.105622

Citations

• Identification and antioxidative mechanism of novel mitochondria-targeted MFG-E8 polypeptides in virtual screening and in vitro study
• Synergistic effects of MFG-E8 and whey protein on mitigating d-galactose-induced sarcopenia through PI3K/AKT/PGC-1α and MAPK/ERK signaling pathways
• Pathophysiology of sarcopenia: Genetic factors and their interplay with environmental factors