Antagonistic pleiotropy and genetic polymorphism: a perspective

1999/02/01 by Philip W Hedrick, Philip W. Hedrick · 20 citations
Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · #Animal Behavior and Reproduction #Genetic diversity and population structure #Genetic Mapping and Diversity in Plants and Animals

paper · pdf · doi:10.1038/sj.hdy.6884400

Cited by

• Anadromy, potamodromy and residency in brown trout Salmo trutta: the role of genes and the environment
• From constraint to opportunity: Relaxing sexual antagonism reveals adaptive potential maintained by balancing selection
• Dominance reversals: the resolution of genetic conflict and maintenance of genetic variation
• Spatially and temporally varying selection on intrapopulation quantitative trait loci for a life history trade‐off in Mimulus guttatus
• Vital rates from the action of mutation accumulation
• Vital Rates from the Action of Mutation Accumulation. [europepmc]
• Pleiotropy of FRIGIDA enhances the potential for multivariate adaptation. [europepmc]
• Naturally segregating loci exhibit epistasis for fitness. [europepmc]
• Nucleotide diversity inflation as a genome-wide response to experimental lifespan extension in Drosophila melanogaster. [europepmc]
• Polymorphism of MHC class IIB in an acheilognathid species, Rhodeus sinensis shaped by historical selection and recombination. [europepmc]
• Balancing selection via life-history trade-offs maintains an inversion polymorphism in a seaweed fly. [europepmc]
• Genotype-environment interaction and the maintenance of genetic variation: an empirical study of Lobelia inflata (Campanulaceae). [europepmc]
• A non-coding indel polymorphism in the fruitless gene of Drosophila melanogaster exhibits antagonistically pleiotropic fitness effects. [europepmc]
• Herbivore-induced defenses are not under phylogenetic constraints in the genus Quercus (oak): Phylogenetic patterns of growth, defense, and storage. [europepmc]
• Differential patterns of diversity at neutral and adaptive loci in endangered Rhodeus pseudosericeus populations. [europepmc]
• Review: Balancing Selection for Deleterious Alleles in Livestock. [europepmc]
• Dominance reversals: the resolution of genetic conflict and maintenance of genetic variation. [europepmc]
• 6Pgdh polymorphism in wild bulb mite populations: prevalence, environmental correlates and life history trade-offs. [europepmc]
• Season-specific dominance broadly stabilizes polymorphism under symmetric and asymmetric multivoltinism. [europepmc]
• Antagonistic pleiotropy plays an important role in governing the evolution and genetic diversity of SARS-CoV-2 [europepmc]