Stuck in traffic: CART cells targeting the tumor microenvironment in hematological malignancies, current advances and future perspectives

2026/07/29 by Jennifer Meyer Feigin, Jennifer M. Feigin, Elizabeth L. Siegler +1
Medicine · #Acute Lymphoblastic Leukemia research #CAR-T cell therapy research #Cutaneous lymphoproliferative disorders research

paper · doi:10.1038/s41375-026-03085-z

openalex publication_date 2026/07/29 · openalex created_date 2026/07/30 · openalex updated_date 2026/07/31

Citations

• IL-12-secreting CD19-targeted cord blood-derived T cells for the immunotherapy of B-cell acute lymphoblastic leukemia
• The CD47-SIRPα Immune Checkpoint
• Determinants of CD19-positive vs CD19-negative relapse after tisagenlecleucel for B-cell acute lymphoblastic leukemia
• GM-CSF disruption in CART cells modulates T cell activation and enhances CART cell anti-tumor activity
• Outcomes of first therapy after CD19-CAR-T treatment failure in large B-cell lymphoma