Mammalian cell protein expression for biopharmaceutical production

2011/09/25 by Jianwei Zhu · 1 citation
Biochemistry, Genetics and Molecular Biology · Medicine · #Monoclonal and Polyclonal Antibodies Research #Protein purification and stability #Viral Infectious Diseases and Gene Expression in Insects

paper · doi:10.1016/j.biotechadv.2011.08.022

openalex publication_date 2011/09/25 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/29

Citations

• Valproic acid enhances recombinant mRNA and protein levels in transiently transfected Chinese hamster ovary cells
• High‐density transfection with HEK‐293 cells allows doubling of transient titers and removes need for a priori DNA complex formation with PEI
• Optimal and consistent protein glycosylation in mammalian cell culture

Cited by

• Adaptive Machine Learning Framework for Optimizing the Affinity Purification of Adeno‐Associated Viral Vectors