The Biology of Cachectin/TNF -- A Primary Mediator of the Host Response

1989/04/01 by B Beutler, Bruce Beutler, Anthony Cerami +1 · 4 citations
Medicine · #Public Health and Nutrition

paper · doi:10.1146/annurev.iy.07.040189.003205

openalex publication_date 1989/04/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/31

Abstract

Exhausted CD8 T (Tex) cells are a distinct cell lineage that arise during chronic infections and cancers in animal models and humans. Tex cells are characterized by progressive loss of effector functions, high and sustained inhibitory receptor expression, ...Read More

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