The Clinical High-Risk State for Psychosis (CHR-P), Version II

2016/10/31 by Paolo Fusar‐Poli, Paolo Fusar-Poli · 2 citations
Arts and Humanities · Medicine · #Bipolar Disorder and Treatment #Mental Health and Psychiatry #Schizophrenia research and treatment

paper · pdf · doi:10.1093/schbul/sbw158

openalex publication_date 2016/10/31 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/29

Abstract

The Clinical High-Risk state for psychosis (CHR-P) paradigm was introduced about 2 decades ago. Over this period of time accumulating knowledge has been gained. Conceptual advancements involve new knowledge into risk enrichment and the impact of recruitment strategies, specificity for prediction of psychotic and nonpsychotic mental disorders and heterogeneity of psychosis risk among the different CHR-P subgroups. The current special issue advances current knowledge on deconstructing the CHR-P paradigm across its 3 subgroups: genetic risk, attenuated psychotic symptoms, and short-lived and remitting psychotic episodes. A conceptual revision of the paradigm (Version II) is suggested and supported by 3 original studies published in this special issue.

Citations

• Prodromal Assessment With the Structured Interview for Prodromal Syndromes and the Scale of Prodromal Symptoms: Predictive Validity, Interrater Reliability, and Training to Reliability
• Mapping the Onset of Psychosis: The Comprehensive Assessment of At-Risk Mental States
• Stress, Coping, Health Practices, and Health Status in Enlisted and Officer Air Force Women with Dependent Children

Cited by

• Doxycycline Use in Adolescent Psychiatric Patients and Risk of Schizophrenia: An Emulated Target Trial
• What causes psychosis? An umbrella review of risk and protective factors

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