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Cortical Surface Diffusion Generative Models

2024/02/07 by Zhenshan Xie, Xie, Zhenshan, Simon Dahan +7 · 1 citation
Computer Science · Neuroscience · #Computer Vision and Pattern Recognition (cs.CV) #FOS: Computer and information sciences #FOS: Electrical engineering #Image and Video Processing (eess.IV) #Medical Image Segmentation Techniques #Visual perception and processing mechanisms #electronic engineering #information engineering

paper · pdf · doi:10.48550/arxiv.2402.04753

openalex publication_date 2024/02/07 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28

Abstract

Cortical surface analysis has gained increased prominence, given its potential implications for neurological and developmental disorders. Traditional vision diffusion models, while effective in generating natural images, present limitations in capturing intricate development patterns in neuroimaging due to limited datasets. This is particularly true for generating cortical surfaces where individual variability in cortical morphology is high, leading to an urgent need for better methods to model brain development and diverse variability inherent across different individuals. In this work, we proposed a novel diffusion model for the generation of cortical surface metrics, using modified surface vision transformers as the principal architecture. We validate our method in the developing Human Connectome Project (dHCP), the results suggest our model demonstrates superior performance in capturing the intricate details of evolving cortical surfaces. Furthermore, our model can generate high-quality realistic samples of cortical surfaces conditioned on postmenstrual age(PMA) at scan.

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