2024/11/18 by Guy A. Richards, Olga Perovic, Adrian Brink · 1 voice
Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · #Antibiotic Resistance in Bacteria #Antibiotic Use and Resistance #Vibrio bacteria research studies
paper · doi:10.1128/cmr.00093-24
openalex created_date 2024/11/18 · openalex publication_date 2024/11/18 · openalex updated_date 2026/07/15
spp. are among the most difficult to treat. Most are resistant to standard antibiotics, and there is difficulty in distinguishing colonizers from pathogens. This mini-review examines the available antibiotics that exhibit activity against these organisms and provides guidance as to which cultures are relevant and how to treat active infections. Antibiograms describing resistance mechanisms and the minimum inhibitory concentration (MIC) are essential to determine which agent or combination of agents should be used after confirmation of infection, utilizing clinical parameters and biomarkers such as procalcitonin. Directed therapy should be prompt as despite its reputation as a colonizer, the attributable mortality is high. However, although combination therapy is advised, no specific combination has definite evidence of superiority.