Ancestry may confound genetic machine learning: Candidate-gene prediction of opioid use disorder as an example

2021/10/11 by Alexander S. Hatoum, Frank R. Wendt, Marco Galimberti +7
Biochemistry, Genetics and Molecular Biology · Medicine · Neuroscience · #Genetic Associations and Epidemiology #Neurotransmitter Receptor Influence on Behavior #Opioid Use Disorder Treatment

paper · doi:10.1016/j.drugalcdep.2021.109115

openalex publication_date 2021/10/11 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/01

Citations

• Transparent Reporting of a multivariable prediction model for Individual Prognosis Or Diagnosis (TRIPOD): the TRIPOD Statement
• A reference panel of 64,976 haplotypes for genotype imputation
• The mutational constraint spectrum quantified from variation in 141,456 humans