Oxygen sensitivity of [FeFe]-hydrogenase: a comparative study of active site mimics inside vs. outside the enzyme

2024/01/01 by Shanika Yadav, Rieke Haas, Esma Birsen Boydas +4 · 1 voice · 2 citations
Energy · Engineering · #Catalysis and Hydrodesulfurization Studies #Electrocatalysts for Energy Conversion #Metalloenzymes and iron-sulfur proteins

paper · pdf · doi:10.1039/d3cp06048a

openalex publication_date 2024/01/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/11

Abstract

is developed. Our study underscores the relevance of model systems in understanding biocatalysis and validates their potential as important tools for elucidating the chemistry of oxygen-induced deactivation of [FeFe]-hydrogenase.

Citations

• Characterization of a putative sensory [FeFe]-hydrogenase provides new insight into the role of the active site architecture
• Hydrogen energy systems: A critical review of technologies, applications, trends and challenges

Cited by

• Subunit fusion unlocks rapid in vitro maturation for slowly activating heterodimeric [FeFe]-hydrogenases
• Probing the Role of Accessory Domains in Oxygen Stability of [FeFe]-Hydrogenases

Discussions

• Proud to see our article on the O2 sensitivity of [FeFe]-hydrogenase from 2024 featured in @pccp.rsc.org's "Women in Physical Chemistry" collection... Not because of Ulf or me, obvsly, but 1st authors [bsky, 10 points, 1 comments]

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