Prohormone cleavage prediction uncovers a non-incretin anti-obesity peptide

2025/03/05 by Laetitia Coassolo, Niels B. Danneskiold-Samsøe, Niels Banhos Danneskiold‐Samsøe +27 · 1 voice · 1 citation
Biochemistry, Genetics and Molecular Biology · Neuroscience · #Receptor Mechanisms and Signaling #Protein Hydrolysis and Bioactive Peptides #Neuropeptides and Animal Physiology

paper · doi:10.1038/s41586-025-08683-y

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Discussions

• 🤷🏻 Zumindest gibt es nun ein neues Peptid (BRP), das den Appetit senkt; ganz ohne GLP-1-Signalweg. 🐁🐖 In Studien mit Mäusen und Minischweinen wirkte es stark, aber ohne die üblichen Ozempic-Nebe [bsky, 10 points, 0 comments]