Brain injury after cardiac arrest: pathophysiology, treatment, and prognosis

2021/10/27 by Claudio Sandroni, Tobias Cronberg, Mypinder Sekhon +1 · 3 citations
Medicine · #Cardiac Arrest and Resuscitation #Traumatic Brain Injury Research #Traumatic Brain Injury and Neurovascular Disturbances

paper · pdf · doi:10.1007/s00134-021-06548-2

openalex publication_date 2021/10/27 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/01

Abstract

Post-cardiac arrest brain injury (PCABI) is caused by initial ischaemia and subsequent reperfusion of the brain following resuscitation. In those who are admitted to intensive care unit after cardiac arrest, PCABI manifests as coma, and is the main cause of mortality and long-term disability. This review describes the mechanisms of PCABI, its treatment options, its outcomes, and the suggested strategies for outcome prediction.

Citations

• Neuron-Specific Enolase Predicts Poor Outcome After Cardiac Arrest and Targeted Temperature Management: A Multicenter Study on 1,053 Patients

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