1971/01/01 by Björn Öbrink, Åke Wasteson
paper · doi:10.1042/bj1210227
The electrostatic interaction of chondroitin sulphate and the chondroitin sulphate–proteoglycan with collagen was studied by chromatography of the glycosaminoglycan and the proteoglycan on a collagen gel. The observed binding between the macromolecules increased with decreasing pH and ionic strength, and was significant under physiological conditions. A study of the interaction between chondroitin sulphate and a preparation of soluble collagen, with a partition-equilibrium technique, afforded similar results.