Resolving native GABAA receptor structures from the human brain

2025/01/22 by Jia Zhou, Colleen M. Noviello, Colleen Noviello +6 · 1 voice
Biochemistry, Genetics and Molecular Biology · Neuroscience · #Neuroscience and Neuropharmacology Research #Nicotinic Acetylcholine Receptors Study #Receptor Mechanisms and Signaling

paper · doi:10.1038/s41586-024-08454-1

openalex publication_date 2025/01/22 · openalex created_date 2025/01/23 · openalex updated_date 2026/08/03

Citations

• UCSF ChimeraX: Structure visualization for researchers, educators, and developers
• Highly accurate protein structure prediction with AlphaFold

Discussions

• This amazing study reconstructed the exact composition of GABA-A receptors from #epilepsy patients using cryo EM: doi.org/10.1038/s415... [bsky, 1 points, 0 comments]