Myelin plasticity in adulthood and aging

2019/11/22 by Timothy W. Chapman, Robert Hill, Robert A. Hill · 1 citation
Neuroscience · #Axon Guidance and Neuronal Signaling #Neurogenesis and neuroplasticity mechanisms #Neuroinflammation and Neurodegeneration Mechanisms

paper · doi:10.1016/j.neulet.2019.134645

openalex publication_date 2019/11/22 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/29

Citations

• Marked loss of myelinated nerve fibers in the human brain with age
• Lifespan trajectory of myelin integrity and maximum motor speed
• Alzheimer's disease as homeostatic responses to age-related myelin breakdown
• Age-related alterations in white matter microstructure measured by diffusion tensor imaging

Cited by

• The Potential of Rehabilitation to Amplify Experience-Induced Myelin Plasticity and Remyelination in Multiple Sclerosis: A Narrative Review