Role of hydroxysteroid (17beta) dehydrogenase type 1 in reproductive tissues and hormone-dependent diseases

2018/08/25 by Taija Heinosalo, Niina Saarinen, Matti Poutanen · 1 citation
Biochemistry, Genetics and Molecular Biology · Medicine · #Estrogen and related hormone effects #Hormonal Regulation and Hypertension #Steroid Chemistry and Biochemistry

paper · doi:10.1016/j.mce.2018.08.004

openalex publication_date 2018/08/25 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/31

Citations

• 17β-Hydroxysteroid dehydrogenases involved in local oestrogen synthesis have prognostic significance in breast cancer
• Plasma level of hydroxysteroid (17-β) dehydrogenase 1 in the second trimester is an independent risk factor for predicting preeclampsia after adjusting for the effects of mean blood pressure, bilateral notching and plasma level of soluble fms-like tyrosine kinase 1/placental growth factor ratio

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• Evolutionarily divergent transcriptomic programs in ovarian folliculogenesis across mice, monkeys and humans