Perfluoroalkyl substance pollutants disrupt microglia function and trigger transcriptional and epigenomic changes

2025/05/24 by Yating Cheng, Jianrong Li, Jian-Rong Li +6
Environmental Science · #Air Quality and Health Impacts #Per- and polyfluoroalkyl substances research #Toxic Organic Pollutants Impact

paper · doi:10.1016/j.tox.2025.154198

openalex publication_date 2025/05/24 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/29

Citations

• Per- and polyfluoroalkyl substances (PFAS) exposure in the U.S. population: NHANES 1999–March 2020
• Per- and Polyfluoroalkyl Substance Toxicity and Human Health Review: Current State of Knowledge and Strategies for Informing Future Research
• Environmental Influences on the Epigenome: Exposure- Associated DNA Methylation in Human Populations
• Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain