2026/07/22 by Anderson Silva Corin, Lidia Cheidde, Lídia Cheidde +6
Neuroscience · Medicine · #Cerebrospinal fluid and hydrocephalus #Neurosurgical Procedures and Complications #Head and Neck Surgical Oncology
paper · pdf · doi:10.1016/j.neuchi.2026.101854
INTRODUCTION: We conducted a systematic review and meta-analysis to compare the effectiveness of shunts with and without anti-siphon devices (ASDs) or other flow-regulating systems in preventing cerebrospinal fluid (CSF) overdrainage and its associated complications. METHODS: Following established guidelines, we searched PubMed, Embase, Scopus, Cochrane, and Web of Science for clinical studies evaluating adult patients diagnosed with NPH who underwent CSF shunting with ASDs or flow-regulating valves, and included a control group of patients with standard CSF shunts lacking such mechanisms. Non-English studies, conference abstracts, and case reports were ineligible. RESULTS: We included seven studies with 928 patients. Although most outcomes showed no statistically significant difference between the intervention and control groups, ASDs had reduced incidences of subdural hygroma (OR = 0.33; p = 0.0368) and subdural hematoma (RR = 0.35; p = 0.0014), indicating a clear benefit in preventing these adverse events. CONCLUSION: ASDs significantly reduced the development of subdural hygroma and subdural hematoma, playing a vital role in preventing neurological sequelae.