vix.ing · top · new · best · stats · spec

Germline natural killer cell receptors modulating the T cell response

2024/11/04 by Laura Mora-Bitria, Becca Asquith · 1 voice
Immunology and Microbiology · #Immune Cell Function and Interaction #IL-33, ST2, and ILC Pathways #T-cell and B-cell Immunology

paper · pdf · doi:10.3389/fimmu.2024.1477991

Abstract

In addition to their central role during innate responses, NK cells regulate adaptive immunity through various mechanisms. A wide array of innate receptors has been involved in the NK cell regulatory function. However, the clinical implications of these regulatory pathways are poorly understood. Here, we review the experimental evidence on the effects of NK cells on T cells and their positive and negative consequences for disease outcome during T cell responses in humans.

Discussions

Related